Day 1 :
BioChemical Engineering Leader University of Virginia USA
Time : 10:00-10:45
Along with a trend toward living a longer, healthier life, more and more patients are looking to physicians to help them achieve a more youthful appearance. The skin's natural aging process manifests contour changes and rhytids secondary to the depletion of subcutaneous fat and the loss of dermal collagen. Traditionally, rejuvenation has been achieved with a face-lift by surgically tightening the skin. Today, a multitude of minimally invasive procedures are aimed at rejuvenation without the risk, recovery time, and expense of major surgery. The development and popularity of BOTOX RTM has opened the door for equally noninvasive, adjunctive treatment of dynamic rhytids and soft tissue augmentation. Soft tissue augmentation has become a popular means of addressing issues such as, contour defects that result from aging, photo-damage, trauma and/or scarification, or disease. A number of filling agents exist in the armamentarium. Therefore, the physician is responsible for knowing which substance is best suited to address a particular defect and the patient or disease process. rnThis presentation will address compositions and methods of use of novel polymeric materials for soft tissue augmentation and drug delivery. An exemplary composition for augmenting soft tissue can include an active ingredient, a carrier, and a cross-linking agent, wherein the carrier is cross-linked where the cross-linking agent and the active ingredient is combined with the cross-linked carrier into a combination having a therapeutic effect. Examples of current and future products will be discussed for this evolving technology that can lead to solutions for tissue regeneration.rn
University of Texas at Dallas, USA
Keynote: A New Generation of Medical Devices Based on Biocompatible Ultrananocrystalline (UNCD®) Diamond Coatings.
Time : 11:00-11:45
Dr. Gurman received his MD from Buenos Aires School of Medicine and has been involved in R&D on micro and nanotechnology for medical applications for the las 7 years. Dr Gurman is the author of 20 publications, and is the editor of 2 books. Dr. Gurman holds one patent and has 2 patent pending.
UNCD films co-developed and patented by O. Auciello and colleagues are synthesized by novel microwave plasma chemical vapor deposition and hot filament chemical vapor deposition techniques using an novel patented Ar-rich/CH4 chemistry that produces films with 2-5 nm grains, thus the name UNCD to distinguish them from nanocrystalline diamond films with 30-100 nm grains. The UNCD films exhibit a unique combination of outstanding mechanical, trtibological, electrical, thermal, and biological properties, which already resulted in industrial components and devices currently commercialized by Advanced Diamond Technologies (company co-founded by Auciello and colleagues in 2003).rnThis talk will focus mainly on the application of UNCD coatings for new generation of medical devices, namely: rnrna) Coating for a microchip implantable in the human retina to restore vision to people blinded by retina disorders to improve biocompatibility of silicon microchips used in implantable electronic componentsrnb) Coating for metallic prostheses including dental implants, hips, and knees to practically eliminate body fluids-induced corrosion and biofouling in current failing metal prostheses rnc) Coating of polymeric devices to improve antifouling propertiesrnd) Development of a new generation of BioMEMS/BioNEMS devices based on UNCD to increase tribological and biological performancerne) Development of piezoelectric multilayer MEMS devices based on biocompatible UNCD/AlN, and UNCD/BiFeO for implantable biosensors to replace piezoactuated BioMEMS based on biologically non-compatible Lead-based piezoelectric PZT rnrnThe biocompatible UNCD coatings are being developed for commercialization in a new generation of implantable medical devices, through a startup company (Original Biomedical Implants (OBI)) co-founded by Auciello and Gurman in 2013.rn